Loss of muscleblind-like 1 promotes invasive mesenchyme formation in endocardial cushions by stimulating autocrine TGFβ3
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چکیده
منابع مشابه
Akt promotes Endocardial-Mesenchyme Transition
Endothelial to mesenchyme transition (EndMT) can be observed during the formation of endocardial cushions from the endocardium, the endothelial lining of the atrioventricular canal (AVC), of the developing heart at embryonic day 9.5 (E9.5). Many regulators of the process have been identified; however, the mechanisms driving the initial commitment decision of endothelial cells to EndMT have been...
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ژورنال
عنوان ژورنال: BMC Developmental Biology
سال: 2012
ISSN: 1471-213X
DOI: 10.1186/1471-213x-12-22